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Immunology

Atacicept

Vera Therapeutics

Dual BAFF/APRIL inhibitor. ORIGIN-3 Phase 3 met primary endpoint (46% proteinuria reduction vs placebo, p<0.0001). BLA filed Nov 2025. FDA decision expected 2026. First dual BAFF/APRIL inhibitor in IgAN.

IgA Nephropathy

Linked Studies

NCT04716231PrimaryACTIVE_NOT_RECRUITINGPHASE3

Atacicept in Subjects With IgA Nephropathy

IgA NephropathyBerger DiseaseUpdated Sep 2025
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atacicept
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