Showing studies related to your query8 results shown

Studies (8 shown)

NCT03155620PHASE2ACTIVE_NOT_RECRUITING

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Sponsor · National Cancer Institute (NCI)Condition · Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin LymphomaIntervention · Biopsy Procedure, Biospecimen CollectionUpdated May 2026
NCT04320888PHASE2ACTIVE_NOT_RECRUITING

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Sponsor · National Cancer Institute (NCI)Condition · Hematopoietic and Lymphatic System Neoplasm, Recurrent EpendymomaIntervention · Computed Tomography, Magnetic Resonance ImagingUpdated May 2026
NCT04759911PHASE2ACTIVE_NOT_RECRUITING

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

Sponsor · M.D. Anderson Cancer CenterCondition · Malignant Thyroid Gland Neoplasm, Poorly Differentiated Thyroid Gland CarcinomaIntervention · Quality-of-Life Assessment, Questionnaire AdministrationUpdated May 2026
NCT07146893EARLY_PHASE1NOT_YET_RECRUITING

Feasibility Study for Repurposing RET Inhibitors

Sponsor · University of OklahomaCondition · Cachexia-Anorexia SyndromeIntervention · Selpercatinib, Strength AssessmentUpdated Jan 2026
NCT03944772PHASE2ACTIVE_NOT_RECRUITING

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Sponsor · AstraZenecaCondition · Non-Small Cell Lung CancerIntervention · Osimertinib, SavolitinibUpdated Jan 2025
NCT05668962PHASE2RECRUITING

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

Sponsor · Massachusetts General HospitalCondition · Thyroid Cancer, Thyroid CarcinomaIntervention · Selpercatinib, Sodium Iodine I-131Updated Dec 2024
NCT05906836PHASE1COMPLETED

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Sponsor · Eli Lilly and CompanyCondition · HealthyIntervention · Rosuvastatin, SelpercatinibUpdated Sep 2025
NCT05364645PHASE2WITHDRAWN

Testing the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung Cancer

Sponsor · SWOG Cancer Research NetworkCondition · Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell CarcinomaIntervention · Carboplatin, PemetrexedUpdated Jul 2024
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