← Back to results
NCT04034095COMPLETED

A Registry Study to Observe Clinical Outcomes of Participants With High-risk Metastatic Hormone-naïve Prostate Cancer in Japan

The Registry to Observe Clinical Outcomes of Patients With High-risk Metastatic Hormone-naïve Prostate Cancer in Japan

Sponsor: Janssen Pharmaceutical K.K.

No open prediction endpoints

Endpoints are classified and published by ProgramSignal analysts.

Request endpoint coverage

Key Facts

Study type
OBSERVATIONAL
Conditions
Prostatic Neoplasms
Interventions
Androgen-deprivation Therapy (ADT), Bicalutamide, Abiraterone, Prednisolone
Enrollment
979 participants
Primary completion
Aug 2024
Study completion
Aug 2024
First posted
Jul 2019
Last updated
Dec 2025

Primary Endpoints (CT.gov)

Percentage of Participants who Achieve Prostate-specific Antigen (PSA) <=0.2 ng/mL Within a Year from Registration

Time frame: 1 year

PSA Progression-free Survival (PSA-PFS)

Time frame: Up to 5 years

Percentage of Participants with PSA-PFS

Time frame: 2 years

Progression-free Survival (PFS)

Time frame: Up to 5 years

Eligibility Criteria

Inclusion Criteria: * Documented diagnosis of metastatic, hormone-naïve prostate cancer (mHNPC) after 1 May 2019 * Should have at least 2 of the 3 following high-risk factors: a Gleason score of greater than or equal to (\>=) 8, at least 3-bone lesions, or the presence of visceral metastasis * Willing to receive androgen-deprivation therapy (ADT) containing regimens for high-risk metastatic, hormone-naïve prostate cancer (mHNPC) in the hospital which have the contract with sponsor for this study, or patient received a regimen containing ADT for high-risk mHNPC * Possess Japanese nationality * Each patient (or their legally acceptable representative) must sign an informed consent form (ICF) indicating that he understands the purpose of, and procedures required for the study and is willing to participate in the study. For dead cases, the ICF can be waived after approved by Independent Ethics Committee/Institutional Review Board (IEC/IRB) Exclusion Criteria: \- has any other active mal

Read full criteria on CT.gov →

✦ Analyst Commentary

Expert commentary on why this trial matters and what to watch for.

Request coverage →

Source

Open on ClinicalTrials.gov