A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

No open prediction endpoints

Endpoints are classified and published by ProgramSignal analysts.

Key Facts

Primary Endpoints (CT.gov)

Secondary Endpoints

Eligibility Criteria

Inclusion Criteria: 1. Patients with relapsed or refractory multiple myeloma who have been treated with a proteasome inhibitor, an IMiD, and an anti-CD38 antibody. Patients who have been treated with at least 2 prior lines of therapy are eligible. Multiple myeloma is defined by the International Myeloma Working Group (IMWG) updated criteria. 2. Patients need to have measurable disease defined by one or more of the following: 1. Serum myeloma (M)-protein greater than or equal to 0.5 g/dL (5 g/L). 2. Urine M-protein greater or equal to 200 mg/24 h. 3. Involved light chain (either kappa or lambda) \>10 mg/dL with an abnormal kappa: lambda ratio 4. Plasmacytoma(s) that is new or definitely increased verified by imaging or biopsy. Increase is defined as a 50% and at least 1 cm increase as measured serially by the sum of the products of the cross-diameters of the measurable lesion. 5. A bone marrow biopsy demonstrating \>30% infiltration of clonal plasma cells. 3. Pat…

✦ Analyst Commentary

Expert commentary on why this trial matters and what to watch for.

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